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Over the past few weeks, the phrase “salmon sperm facial” has been everywhere - trending across beauty pages and timelines.
Much of the interest was sparked by Saman Javed’s beautifully written, intelligent feature in Hyphen Online, which explored both the science and sensation behind Polynucleotide injections.
At Skin & Sanctuary, we read it with admiration - and a smile. It’s rare to see a journalist capture the nuance of regenerative aesthetics so clearly. We did briefly wonder whether we should have invited Saman in to experience Polynucleotides herself… after all, there’s always a benefit to a little collagen banking.
But when someone is already do beautiful and feels confident and radiant in their own skin - as Saman so evidently does - why add something just for the sake of it? That, too, is part of our philosophy.
What Polynucleotides Actually Are
Despite the viral nickname, Polynucleotides are far from a fad. They’re a regenerative injectable treatment that restores skin health at a cellular level.
Derived from highly purified DNA fragments - typically sourced from salmon, whose DNA closely mirrors our own - these molecules stimulate repair, improve hydration, and reduce inflammation.
Think of them as a reset button for tired skin cells. They don’t freeze, fill, or change expression - they help your skin behave the way it used to: stronger, smoother, more resilient.
How Polynucleotides Work
Injected just beneath the surface, Polynucleotides act as biological messengers, encouraging fibroblasts (the skin cells responsible for collagen and elastin) to rebuild from within.
They support hydration, refine texture, and calm inflammation - particularly around delicate areas such as the eyes, neck, and jawline.
At Skin & Sanctuary, we often describe them as intelligent skin repair in a syringe. They fit seamlessly within our regenerative philosophy: strengthening before sculpting.
The Experience at Skin & Sanctuary
Our clinicians - including Dr Mayoni Gooneratne and Dr Jannany Nadarajah who are both mentioned in the article - have been working with Polynucleotides for some time, refining techniques to achieve results that feel subtle, balanced, and entirely natural.
Each treatment begins with a consultation, where we assess skin health, lifestyle, and goals. For most patients, a course of three sessions, spaced two to three weeks apart, builds a long-term collagen reserve.
You may notice an early glow within days, but the true transformation appears gradually over six to twelve weeks as the skin begins to regenerate itself.
Why This Treatment Feels Different
Polynucleotides don’t disguise ageing - they support the structures that prevent it.
Unlike fillers or wrinkle relaxers, they improve function, not just form. This makes them ideal for anyone who wants to look rested, not “done.”
They’re also incredibly versatile: suitable for younger patients who want to protect their skin, as well as for those noticing dullness, fine lines, or early laxity.
And yes - they’re safe. The DNA material used is ultra-purified and sterilised, leaving only what the body recognises as its own.
Our Philosophy: Regeneration First
We’ve always believed that good medicine starts with honesty.
Sometimes the right decision is to begin treatment; other times, it’s to pause and simply maintain what already looks and feels good.
That’s why we appreciate Saman Javed’s piece so much, it represents the kind of intelligent conversation our field needs more of: one rooted in curiosity, not vanity.
Regenerative treatments like Polynucleotides are powerful tools, but they’re not obligatory. They’re an option — a way to future-proof your skin if it feels right for you.
Interested in Learning More?
If the Hyphen Online feature sparked your curiosity, we’d love to talk.
A consultation is the best place to understand whether Polynucleotides would genuinely benefit your skin — or whether your current routine is already serving you beautifully.
→ Book a consultation or call 020 3952 8010
No pressure, just clarity - because confidence begins with understanding.